January 20, 2020 5 min read

What Is Laxogenin?

5-Alpha-Hydroxy Laxogenin is a natural steroidial sapogenin derived from the Asian plant Smilax Sieboldii. This compound belongs to the group of brassinosteroids also known as plant hormones.

This is why you'll find that Laxogenin is often referred to as the plant steroid. However, it should not be confused with steroid hormones or prohormones because they are completely different. Remember, it is naturally derived and therefore does not mess with your body's natural hormones.

The Benefits Of Laxogenin

Let's move on to why you started researching about Laxogenin in the first place - the potential benefits. As you might already know, this compound is extremely popular amongst bodybuilders and other athletes. You'll find that there are a lot of positive user experiences of those who have used it to help with muscle growth.

Based on anecdotal experience, 5-Alpha-Hydroxy Laxogenin could potentially help with:

  • Supporting muscle growth
  • Improving protein synthesis
  • Reduce blood sugar levels
  • Boosting muscle recovery

Of course, this makes it a very interesting supplement to use for every serious athlete out there. Especially since it is a natural compound that does not mess with the endrocine system meaning post cycle therapy is not required.

Clinical studies have shown brassinosteroids to be quite interesting. But, further research needs to be performed to back up these claims.

With that being said, the many positive user reviews have had a huge impact on Laxogenin's popularity in the bodybuilding community.

Laxogenin Dosage And Cycle

If the benefits sound appealing to you and you are considering using this product, it's essential to know how to use it. Just as with many bodybuilding supplements, it works the best at a specific dosage and cycle length.

The optimal Laxogenin dosage is said to be between 100-200mg per day. I can also personally vouch for this, as I was making good progress with 200mg per day.


Perhaps if it's your first ride with a Laxogenin supplement, try starting at 100mg per day. From there, you can gradually build the dosage to 200mg per day. It is advised to dose it once a day, preferably with a meal.

Based on anecdotal experiences, most people run it for 6 to 12 weeks. I found that running longer cycles resulted in better gains, so I always go for at least 10 to 12 weeks.

Since it does not mess with your body's natural hormones, it's often run for more extended periods. Many users stack this compound with other muscle building supplements such as Arachidone and Rebirth. Stacking them together creates a very potent natural muscle building stack.

Will It Cause Side Effects?

5-Alpha Hydroxy Laxogenin is said to have anabolic properties which means it could help you with accelerating muscle growth. Based on online user reviews, it is said that this compound is pretty much safe to use. Some users have reported headaches when using it at higher dosages.

It is also important to know that this compound does not mess with your testosterone levels. Therefore, it will not require a Post Cycle Therapy. It's the perfect muscle building supplement for those that want in results in a safe and responsible way.

Because it seems to have little to no side effects, most users decide to run Laxogenin for longer periods of time. It's not unheard of for bodybuilders to use it for 3 to 4 months.

We always advise that you consult with a healthcare professional before starting a nutritional supplement.

What Others Are Saying About Laxogenin

I'm a massive fan of this ingredient and the benefits I have experienced from it. Here are a few more user reviews of people that have used Annihilate, our laxogenin supplement.



As you can see, I'm not the only one that has benefited from using it. You can read more reviews on Annihilate by visiting the product page.

Laxogenin Supplements

This compound has grown out to be a very popular muscle building supplement. Some even consider it to be one of the best legal steroids.

Therefore, you'll find that there are a lot of different supplements available. Each supplement has it's own dosage of 5-Alpha Hydroxy, usually between 25 to 75mg.

But, we've decided to do things a little differently - we wanted our customers to get a high-quality product and their money's worth.

laxogenin supplement

Allow us to introduce you to our laxogenin supplement; Annihilate. It's one of our best-selling muscle-building supplements.

Annihilate contains 60 capsules with 100mg of 5-alpha hydroxy laxogenin per capsule.

Comparing this to other alternatives on the market, you're getting near double to triple the amount of active ingredient for the same price. Check out the supplement facts below, and you'll see that we aren't kidding.


It is a lot more compared to most products out there. With one bottle, you'll be able to run an 8-week cycle at 100mg per day. Experienced users can consider purchasing two bottles to run an 8-week cycle at 200mg per day.

You can also consider stacking it with an epicatechin supplement. Our product Epitech contains it at 250mg per serving.

A muscle building stack is an excellent way of boosting progress naturally. We've put together several popular supplements to create stacks; you can visit them here.

Frequently Asked Questions

How Much Laxogenin Should I Take?

It advised to start out with 100mg per day. From there it is possible to build up the dosage to 200mg per day.

Annihilate contains 100mg per capsule, which means you will start off by taking just one capsule per day.

When To Take Laxogenin?

Most users take their dosage in the morning with a meal or pre-workout. But, the timing isn’t really important when taking Laxogenin. Make sure to take it consistently and to not skip a dose.

Should I Stack This Supplement?

Yes, you can choose to stack this compound with other muscle building supplements. Our most popular stack is the Huge Mass Stack. It combines Annihilate, Arachidone, Enhance and Epitech.

You can also combine it with a pre-workout such as Wrecked to help you during workouts.

How Long Should I Take Laxogenin?

Generally, it is advised to run it for 6 to 12 weeks. How long exactly you want to run it will come down to your personal goals.

What Age Should You Be To Take Laxogenin?

It is advised to be at least 18 years old before taking any type of supplement.

Does Laxogenin Work?

Based on the many positive user experiences found online, it is definitely one of the most promising muscle builders currently on the market. With that being said, it is also extremely important to track your macros and workout several times a week.


5-Alpha Hydroxy Laxogenin is an excellent anabolic supplement that could help you reach your goals faster. It is a plant derived compound and has little to no side effects.

Anecdotal experiences have shown it to support muscle growth, recovery, protein synthesis, and nitrogen retention. This is backed up by countless users who have successfully used it to help them get closer to the physique they want.

When gaining new muscle mass it's very important that you have your diet, training, and sleeping in check. If you need help with calculating your macro's please use this helpful macro calculator.

It's an effective supplement for those who want to start taking your physique and performance to the next level safely and responsibly. Also, make sure to read our best pre workout article.

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